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ZEB1/NuRD complex suppresses TBC1D2b to stimulate E-cadherin internalization and promote metastasis in lung cancer
Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death worldwide, due in part to the propensity of lung cancer to metastasize. Aberrant epithelial-to-mesenchymal transition (EMT) is a proposed model for the initiation of metastasis. During EMT cell-cell adhesion is reduced a...
Autores principales: | Manshouri, Roxsan, Coyaud, Etienne, Kundu, Samrat T., Peng, David H., Stratton, Sabrina A., Alton, Kendra, Bajaj, Rakhee, Fradette, Jared J., Minelli, Rosalba, Peoples, Michael D., Carugo, Alessandro, Chen, Fengju, Bristow, Christopher, Kovacs, Jeffrey J., Barton, Michelle C., Heffernan, Tim, Creighton, Chad J., Raught, Brian, Gibbons, Don L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851102/ https://www.ncbi.nlm.nih.gov/pubmed/31719531 http://dx.doi.org/10.1038/s41467-019-12832-z |
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