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Activation of PXR by alantolactone ameliorates DSS-induced experimental colitis via suppressing NF-κB signaling pathway
Alantolactone (ALA) is a sesquiterpene lactone with potent anti-inflammatory activity. However, the effect of ALA on intestinal inflammation remains largely unknown. The present study demonstrated that ALA significantly ameliorated the clinical symptoms of dextran sulfate sodium (DSS)-induced mice c...
Autores principales: | Ren, Yijing, Yue, Bei, Ren, Gaiyan, Yu, Zhilun, Luo, Xiaoping, Sun, Aning, Zhang, Jingjing, Han, Mengqing, Wang, Zhengtao, Dou, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851188/ https://www.ncbi.nlm.nih.gov/pubmed/31719637 http://dx.doi.org/10.1038/s41598-019-53305-z |
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