Cargando…
Cabozantinib (XL184) and R428 (BGB324) Inhibit the Growth of Esophageal Squamous Cell Carcinoma (ESCC)
Esophageal squamous cell carcinoma (ESCC) is a deadly disease for which no effective targeted therapeutic agent has been approved. Both AXL and c-MET have been reported to be independent prognostic factors for ESCC. Thus, inhibitors of AXL/c-MET might have great potential as targeted therapy for ESC...
Autores principales: | Yang, Pei-Wen, Liu, Yu-Cheng, Chang, Ya-Han, Lin, Ching-Ching, Huang, Pei-Ming, Hua, Kuo-Tai, Lee, Jang-Ming, Hsieh, Min-Shu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851194/ https://www.ncbi.nlm.nih.gov/pubmed/31781483 http://dx.doi.org/10.3389/fonc.2019.01138 |
Ejemplares similares
-
The role of AXL and the in vitro activity of the receptor tyrosine kinase inhibitor BGB324 in Ewing sarcoma
por: Fleuren, Emmy D.G., et al.
Publicado: (2014) -
A phase Ib/II study of cabozantinib (XL184) with or without erlotinib in patients with non-small cell lung cancer
por: Wakelee, Heather A., et al.
Publicado: (2017) -
Clinical Activity of Single-Agent Cabozantinib (XL184), a Multi-receptor Tyrosine Kinase Inhibitor, in Patients with Refractory Soft-Tissue Sarcomas
por: O'Sullivan Coyne, Geraldine, et al.
Publicado: (2022) -
Cisplatin and Pemetrexed Activate AXL and AXL Inhibitor BGB324 Enhances Mesothelioma Cell Death from Chemotherapy
por: Oien, Derek B., et al.
Publicado: (2018) -
High-CLDN4 ESCC cells harbor stem-like properties and indicate for
poor concurrent chemoradiation therapy response in esophageal squamous cell
carcinoma
por: Lin, Cheng-Han, et al.
Publicado: (2019)