Unpredictable Nanoparticle Retention in Commonly Used Plastic Syringes Introduces Dosage Uncertainties That May Compromise the Accuracy of Nanomedicine and Nanotoxicology Studies

In recent animal experiments with suspensions of radiolabeled TiO(2) nanoparticles large and highly variable radioactivity fractions were retained in disposable plastic syringes. After unloading between 10% and up to 70% of the loaded dose were still present in the syringes. As a consequence the eff...

Descripción completa

Detalles Bibliográficos
Autores principales: Holzwarth, Uwe, Cossío, Unai, Llop, Jordi, Kreyling, Wolfgang G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851237/
https://www.ncbi.nlm.nih.gov/pubmed/31780932
http://dx.doi.org/10.3389/fphar.2019.01293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851237/
https://www.ncbi.nlm.nih.gov/pubmed/31780932
http://dx.doi.org/10.3389/fphar.2019.01293

Ejemplares similares