Identification of Novel Microsatellite Markers Flanking the SMN1 and SMN2 Duplicated Region and Inclusion Into a Single-Tube Tridecaplex Panel for Haplotype-Based Preimplantation Genetic Testing of Spinal Muscular Atrophy

Preimplantation genetic testing for the monogenic disorder (PGT-M) spinal muscular atrophy (SMA) is significantly improved by supplementation of SMN1 deletion detection with marker-based linkage analysis. To expand the availability of informative markers for PGT-M of SMA, we identified novel non-dup...

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Detalles Bibliográficos
Autores principales: Zhao, Mingjue, Lian, Mulias, Cheah, Felicia S.H., Tan, Arnold S.C., Agarwal, Anupriya, Chong, Samuel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851269/
https://www.ncbi.nlm.nih.gov/pubmed/31781167
http://dx.doi.org/10.3389/fgene.2019.01105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851269/
https://www.ncbi.nlm.nih.gov/pubmed/31781167
http://dx.doi.org/10.3389/fgene.2019.01105

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