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Activation of RNase L in Egyptian Rousette Bat-Derived RoNi/7 Cells Is Dependent Primarily on OAS3 and Independent of MAVS Signaling

Bats are reservoirs for many RNA viruses that are highly pathogenic in humans yet relatively apathogenic in the natural host. It has been suggested that differences in innate immunity are responsible. The antiviral OAS-RNase L pathway is well characterized in humans, but there is little known about...

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Detalles Bibliográficos
Autores principales:	Li, Yize, Dong, Beihua, Wei, Zuzhang, Silverman, Robert H., Weiss, Susan R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851283/ https://www.ncbi.nlm.nih.gov/pubmed/31719180 http://dx.doi.org/10.1128/mBio.02414-19

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