Atomic-resolution crystal structures of the immune protein conglutinin from cow reveal specific interactions of its binding site with N-acetylglucosamine

Bovine conglutinin is an immune protein that is involved in host resistance to microbes and parasites and interacts with complement component iC3b, agglutinates erythrocytes, and neutralizes influenza A virus. Here, we determined the high-resolution (0.97–1.46 Å) crystal structures with and without...

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Detalles Bibliográficos
Autores principales: Paterson, Janet M., Shaw, Amy J., Burns, Ian, Dodds, Alister W., Prasad, Alpana, Reid, Ken B., Greenhough, Trevor J., Shrive, Annette K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851296/
https://www.ncbi.nlm.nih.gov/pubmed/31562242
http://dx.doi.org/10.1074/jbc.RA119.010271

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