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Toll-like receptor 2–dependent endosomal signaling by Staphylococcus aureus in monocytes induces type I interferon and promotes intracellular survival

Pathogen activation of innate immune pattern recognition receptors (PRRs) such as Toll-like receptors (TLRs) stimulates cellular signaling pathways. This often leads to outcomes that contribute to pathogen clearance. Alternatively, activation of specific PRR pathways can aid pathogen survival. The h...

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Detalles Bibliográficos
Autores principales:	Musilova, Jana, Mulcahy, Michelle E., Kuijk, Marieke M., McLoughlin, Rachel M., Bowie, Andrew G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851302/ https://www.ncbi.nlm.nih.gov/pubmed/31558608 http://dx.doi.org/10.1074/jbc.RA119.009302

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