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The C-terminal dimerization domain of the respiratory mucin MUC5B functions in mucin stability and intracellular packaging before secretion

Mucin 5B (MUC5B) has an essential role in mucociliary clearance that protects the pulmonary airways. Accordingly, knowledge of MUC5B structure and its interactions with itself and other proteins is critical to better understand airway mucus biology and improve the management of lung diseases such as...

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Detalles Bibliográficos
Autores principales:	Ridley, Caroline, Lockhart-Cairns, Michael P., Collins, Richard F., Jowitt, Thomas A., Subramani, Durai B., Kesimer, Mehmet, Baldock, Clair, Thornton, David J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2019
Materias:	Glycobiology and Extracellular Matrices
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851316/ https://www.ncbi.nlm.nih.gov/pubmed/31570524 http://dx.doi.org/10.1074/jbc.RA119.010771

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