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Functional Screening Identifies MicroRNA Regulators of Corin Activity and Atrial Natriuretic Peptide Biogenesis

Atrial natriuretic peptide (ANP) represents an attractive therapeutic target in hypertension and heart failure. The biologically active form of ANP is produced by the cardiac serine protease corin, and modulation of its activity might therefore represent a novel approach for ANP augmentation. MicroR...

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Detalles Bibliográficos
Autores principales:	Celik, Selvi, Karbalaei-Sadegh, Mardjaneh, Rådegran, Göran, Smith, J. Gustav, Gidlöf, Olof
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851346/ https://www.ncbi.nlm.nih.gov/pubmed/31548261 http://dx.doi.org/10.1128/MCB.00271-19

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