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Methylation-related metabolic effects of D4 dopamine receptor expression and activation
D4 dopamine receptor (D4R) activation uniquely promotes methylation of plasma membrane phospholipids, utilizing folate-derived methyl groups provided by methionine synthase (MS). We evaluated the impact of D4R expression on folate-dependent phospholipid methylation (PLM) and MS activity, as well as...
Autores principales: | Hodgson, Nathaniel W., Waly, Mostafa I., Trivedi, Malav S., Power-Charnitsky, Verna-Ann, Deth, Richard C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851363/ https://www.ncbi.nlm.nih.gov/pubmed/31719518 http://dx.doi.org/10.1038/s41398-019-0630-3 |
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