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Early and long‐term results of surgery for secondary mitral regurgitation with a damaged heart

BACKGROUND: Surgery for secondary mitral regurgitation is still controversial, especially when the left ventricle is damaged. The Mitra Clip has been shown to be safe and effective for certain patient groups but does not offer superior control of mitral regurgitation compared with the surgery. If pe...

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Autores principales: Kitamura, Hideki, Kagase, Ai, Koyama, Yutaka, Tamaki, Mototsugu, Kawaguchi, Yasuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851538/
https://www.ncbi.nlm.nih.gov/pubmed/31269298
http://dx.doi.org/10.1111/jocs.14147
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author Kitamura, Hideki
Kagase, Ai
Koyama, Yutaka
Tamaki, Mototsugu
Kawaguchi, Yasuhiko
author_facet Kitamura, Hideki
Kagase, Ai
Koyama, Yutaka
Tamaki, Mototsugu
Kawaguchi, Yasuhiko
author_sort Kitamura, Hideki
collection PubMed
description BACKGROUND: Surgery for secondary mitral regurgitation is still controversial, especially when the left ventricle is damaged. The Mitra Clip has been shown to be safe and effective for certain patient groups but does not offer superior control of mitral regurgitation compared with the surgery. If performed safely, the surgery can provide greater benefits over the long‐term. The objective of this study was to retrospectively investigate the early and long‐term results of mitral valve surgery for secondary mitral valve regurgitation with a damaged, dilated left ventricle. METHODS: Patients with ejection fraction <40% and left ventricular end‐diastolic/systolic diameter >50/40 mm who underwent mitral valve surgery for secondary mitral regurgitation were investigated retrospectively. RESULTS: The mean age of the 80 identified cases was 65.7 years, and 63 patients were male. Preoperative echocardiograms showed a mean ejection fraction of 25.2% and mean left ventricular diameters in diastole/systole of 64.5/56.9 mm, respectively. Mitral valve replacement was performed in 39 cases, and mitral valve plasty in 41 cases. The most common concomitant procedures were coronary artery bypass grafting and tricuspid valve surgery (41.3% each). Mitral regurgitation improved significantly from 3.5 to 0.83, and no operative or in‐hospital deaths were encountered. Long‐term results showed actual 1‐, 3‐ and 5‐year survival rates of 93.1%, 80.0%, and 64.7%, respectively (mean follow‐up, 1264 days). CONCLUSIONS: Early results of this study were good and long‐term results were acceptable. Our results suggest that mitral valve surgery is feasible for secondary mitral valve regurgitation even in dilated, damaged hearts.
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spelling pubmed-68515382019-11-18 Early and long‐term results of surgery for secondary mitral regurgitation with a damaged heart Kitamura, Hideki Kagase, Ai Koyama, Yutaka Tamaki, Mototsugu Kawaguchi, Yasuhiko J Card Surg Original Articles BACKGROUND: Surgery for secondary mitral regurgitation is still controversial, especially when the left ventricle is damaged. The Mitra Clip has been shown to be safe and effective for certain patient groups but does not offer superior control of mitral regurgitation compared with the surgery. If performed safely, the surgery can provide greater benefits over the long‐term. The objective of this study was to retrospectively investigate the early and long‐term results of mitral valve surgery for secondary mitral valve regurgitation with a damaged, dilated left ventricle. METHODS: Patients with ejection fraction <40% and left ventricular end‐diastolic/systolic diameter >50/40 mm who underwent mitral valve surgery for secondary mitral regurgitation were investigated retrospectively. RESULTS: The mean age of the 80 identified cases was 65.7 years, and 63 patients were male. Preoperative echocardiograms showed a mean ejection fraction of 25.2% and mean left ventricular diameters in diastole/systole of 64.5/56.9 mm, respectively. Mitral valve replacement was performed in 39 cases, and mitral valve plasty in 41 cases. The most common concomitant procedures were coronary artery bypass grafting and tricuspid valve surgery (41.3% each). Mitral regurgitation improved significantly from 3.5 to 0.83, and no operative or in‐hospital deaths were encountered. Long‐term results showed actual 1‐, 3‐ and 5‐year survival rates of 93.1%, 80.0%, and 64.7%, respectively (mean follow‐up, 1264 days). CONCLUSIONS: Early results of this study were good and long‐term results were acceptable. Our results suggest that mitral valve surgery is feasible for secondary mitral valve regurgitation even in dilated, damaged hearts. John Wiley and Sons Inc. 2019-07-03 2019-10 /pmc/articles/PMC6851538/ /pubmed/31269298 http://dx.doi.org/10.1111/jocs.14147 Text en © 2019 The Authors. Journal of Cardiac Surgery Published by Wiley Periodicals, Inc. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Articles
Kitamura, Hideki
Kagase, Ai
Koyama, Yutaka
Tamaki, Mototsugu
Kawaguchi, Yasuhiko
Early and long‐term results of surgery for secondary mitral regurgitation with a damaged heart
title Early and long‐term results of surgery for secondary mitral regurgitation with a damaged heart
title_full Early and long‐term results of surgery for secondary mitral regurgitation with a damaged heart
title_fullStr Early and long‐term results of surgery for secondary mitral regurgitation with a damaged heart
title_full_unstemmed Early and long‐term results of surgery for secondary mitral regurgitation with a damaged heart
title_short Early and long‐term results of surgery for secondary mitral regurgitation with a damaged heart
title_sort early and long‐term results of surgery for secondary mitral regurgitation with a damaged heart
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851538/
https://www.ncbi.nlm.nih.gov/pubmed/31269298
http://dx.doi.org/10.1111/jocs.14147
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