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A novel percutaneous transhepatic treatment of a benign bile duct stricture – a pilot study

AIM: To assess the effectiveness and outcome of repeated percutaneous transhepatic balloon dilatation combined with targeted intramucosal corticosteroid injection in patients with benign biliary stricture. METHODS: This single-center pilot study, conducted between February 2014 and June 2016, involv...

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Detalles Bibliográficos
Autores principales: Huszár, Orsolya, Szijarto, Attila, Tihanyi, Tibor, Harsányi, László, Szücs, Ákos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Croatian Medical Schools 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852140/
https://www.ncbi.nlm.nih.gov/pubmed/31686453
http://dx.doi.org/10.3325/cmj.2019.60.397
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author Huszár, Orsolya
Szijarto, Attila
Tihanyi, Tibor
Harsányi, László
Szücs, Ákos
author_facet Huszár, Orsolya
Szijarto, Attila
Tihanyi, Tibor
Harsányi, László
Szücs, Ákos
author_sort Huszár, Orsolya
collection PubMed
description AIM: To assess the effectiveness and outcome of repeated percutaneous transhepatic balloon dilatation combined with targeted intramucosal corticosteroid injection in patients with benign biliary stricture. METHODS: This single-center pilot study, conducted between February 2014 and June 2016, involved five patients with benign biliary stricture (4 men and 1 woman, mean age 58.2 years). The study included only patients in whom previous surgical or/and non-surgical treatments failed or could not be performed due to patients’ medical history and local status. RESULTS: We successfully developed an alternative treatment for patients with benign biliary stricture and performed it without side effects. There were no major complications, and the only one minor complication was cholangitis. In the median follow-up period of 30.24 months (range 14.5 to 44.6 months), no re-occlusion was detected. The disease-free survival, calculated after excluding the first patient (who died of heart attack), was 34.175 months. CONCLUSION: Percutaneous transhepatic corticosteroid injection combined with balloon dilatation could provide an alternative method for the treatment of benign biliary strictures that is effective in the long term and results in positive outcomes.
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spelling pubmed-68521402019-11-22 A novel percutaneous transhepatic treatment of a benign bile duct stricture – a pilot study Huszár, Orsolya Szijarto, Attila Tihanyi, Tibor Harsányi, László Szücs, Ákos Croat Med J Research Article AIM: To assess the effectiveness and outcome of repeated percutaneous transhepatic balloon dilatation combined with targeted intramucosal corticosteroid injection in patients with benign biliary stricture. METHODS: This single-center pilot study, conducted between February 2014 and June 2016, involved five patients with benign biliary stricture (4 men and 1 woman, mean age 58.2 years). The study included only patients in whom previous surgical or/and non-surgical treatments failed or could not be performed due to patients’ medical history and local status. RESULTS: We successfully developed an alternative treatment for patients with benign biliary stricture and performed it without side effects. There were no major complications, and the only one minor complication was cholangitis. In the median follow-up period of 30.24 months (range 14.5 to 44.6 months), no re-occlusion was detected. The disease-free survival, calculated after excluding the first patient (who died of heart attack), was 34.175 months. CONCLUSION: Percutaneous transhepatic corticosteroid injection combined with balloon dilatation could provide an alternative method for the treatment of benign biliary strictures that is effective in the long term and results in positive outcomes. Croatian Medical Schools 2019-10 /pmc/articles/PMC6852140/ /pubmed/31686453 http://dx.doi.org/10.3325/cmj.2019.60.397 Text en Copyright © 2019 by the Croatian Medical Journal. All rights reserved. http://creativecommons.org/licenses/by/2.5/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Huszár, Orsolya
Szijarto, Attila
Tihanyi, Tibor
Harsányi, László
Szücs, Ákos
A novel percutaneous transhepatic treatment of a benign bile duct stricture – a pilot study
title A novel percutaneous transhepatic treatment of a benign bile duct stricture – a pilot study
title_full A novel percutaneous transhepatic treatment of a benign bile duct stricture – a pilot study
title_fullStr A novel percutaneous transhepatic treatment of a benign bile duct stricture – a pilot study
title_full_unstemmed A novel percutaneous transhepatic treatment of a benign bile duct stricture – a pilot study
title_short A novel percutaneous transhepatic treatment of a benign bile duct stricture – a pilot study
title_sort novel percutaneous transhepatic treatment of a benign bile duct stricture – a pilot study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852140/
https://www.ncbi.nlm.nih.gov/pubmed/31686453
http://dx.doi.org/10.3325/cmj.2019.60.397
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