Altered immunoreactivity of ErbB4, a causative gene product for ALS19, in the spinal cord of patients with sporadic ALS

ErbB4 is the protein implicated in familial amyotrophic lateral sclerosis (ALS), designated as ALS19. ErbB4 is a receptor tyrosine kinase activated by its ligands, neuregulins (NRG), and plays an essential role in the function and viability of motor neurons. Mutations in the ALS19 gene lead to the r...

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Detalles Bibliográficos
Autores principales: Takahashi, Yuji, Uchino, Akiko, Shioya, Ayako, Sano, Terunori, Matsumoto, Chihiro, Numata‐Uematsu, Yurika, Nagano, Seiichi, Araki, Toshiyuki, Murayama, Shigeo, Saito, Yuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852233/
https://www.ncbi.nlm.nih.gov/pubmed/31124187
http://dx.doi.org/10.1111/neup.12558

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