Autophagy contributes to BMP type 2 receptor degradation and development of pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) is characterised by an increase in mean pulmonary arterial pressure which almost invariably leads to right heart failure and premature death. More than 70% of familial PAH and 20% of idiopathic PAH patients carry heterozygous mutations in the bone morphogenetic...

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Detalles Bibliográficos
Autores principales: Gomez‐Puerto, Maria Catalina, van Zuijen, Iris, Huang, Christopher JZ, Szulcek, Robert, Pan, Xiaoke, van Dinther, Maarten AH, Kurakula, Kondababu, Wiesmeijer, Catharina C, Goumans, Marie‐Jose, Bogaard, Harm‐Jan, Morrell, Nicholas W, Rana, Amer Ahmed, ten Dijke, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2019
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852495/
https://www.ncbi.nlm.nih.gov/pubmed/31257577
http://dx.doi.org/10.1002/path.5322

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