Frontline Science: Endotoxin‐induced immunotolerance is associated with loss of monocyte metabolic plasticity and reduction of oxidative burst

Secondary infections are a major complication of sepsis and associated with a compromised immune state, called sepsis‐induced immunoparalysis. Molecular mechanisms causing immunoparalysis remain unclear; however, changes in cellular metabolism of leukocytes have been linked to immunoparalysis. We in...

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Detalles Bibliográficos
Autores principales: Grondman, Inge, Arts, Rob J. W., Koch, Rebecca M., Leijte, Guus P., Gerretsen, Jelle, Bruse, Niklas, Kempkes, Rosalie W. M., ter Horst, Rob, Kox, Matthijs, Pickkers, Peter, Netea, Mihai G., Gresnigt, Mark S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Spotlight on Leading Edge Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852552/
https://www.ncbi.nlm.nih.gov/pubmed/31169935
http://dx.doi.org/10.1002/JLB.5HI0119-018R

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852552/
https://www.ncbi.nlm.nih.gov/pubmed/31169935
http://dx.doi.org/10.1002/JLB.5HI0119-018R

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