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Hyperuricaemia is associated with dyslipidemia but not HbA1c among type 2 diabetes mellitus patients in Botswana
Medical records and residual samples from 334 type 2 diabetes mellitus patients attending a clinic in Gaborone, Botswana, during the period September–December 2016 were analysed for the effects of hyperuricaemia on biochemical markers of adverse outcomes. The patients were stratified as having hyper...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AOSIS
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852606/ https://www.ncbi.nlm.nih.gov/pubmed/31745455 http://dx.doi.org/10.4102/ajlm.v8i1.786 |
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author | Gobusamang, Ellen Nyepetsi, Naledi G. Motswaledi, Modisa S. Kasvosve, Ishmael |
author_facet | Gobusamang, Ellen Nyepetsi, Naledi G. Motswaledi, Modisa S. Kasvosve, Ishmael |
author_sort | Gobusamang, Ellen |
collection | PubMed |
description | Medical records and residual samples from 334 type 2 diabetes mellitus patients attending a clinic in Gaborone, Botswana, during the period September–December 2016 were analysed for the effects of hyperuricaemia on biochemical markers of adverse outcomes. The patients were stratified as having hyperuricaemia (> 400 µmol/L) or normal serum uric acid (≤ 400 µmol/L). We compared glycated haemoglobin, triglycerides, low-density lipoprotein-cholesterol, high-density lipoprotein-cholesterol, total cholesterol and serum creatinine between the two serum uric acid categories. Hyperuricaemia was detected in 28% of patients (95% confidence interval 23.1–32.9) and was associated with increased serum triglycerides, triglyceride to high-density lipoprotein-cholesterol ratio and creatinine concentration, but not with glycated haemoglobin. |
format | Online Article Text |
id | pubmed-6852606 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | AOSIS |
record_format | MEDLINE/PubMed |
spelling | pubmed-68526062019-11-19 Hyperuricaemia is associated with dyslipidemia but not HbA1c among type 2 diabetes mellitus patients in Botswana Gobusamang, Ellen Nyepetsi, Naledi G. Motswaledi, Modisa S. Kasvosve, Ishmael Afr J Lab Med Brief Report Medical records and residual samples from 334 type 2 diabetes mellitus patients attending a clinic in Gaborone, Botswana, during the period September–December 2016 were analysed for the effects of hyperuricaemia on biochemical markers of adverse outcomes. The patients were stratified as having hyperuricaemia (> 400 µmol/L) or normal serum uric acid (≤ 400 µmol/L). We compared glycated haemoglobin, triglycerides, low-density lipoprotein-cholesterol, high-density lipoprotein-cholesterol, total cholesterol and serum creatinine between the two serum uric acid categories. Hyperuricaemia was detected in 28% of patients (95% confidence interval 23.1–32.9) and was associated with increased serum triglycerides, triglyceride to high-density lipoprotein-cholesterol ratio and creatinine concentration, but not with glycated haemoglobin. AOSIS 2019-11-07 /pmc/articles/PMC6852606/ /pubmed/31745455 http://dx.doi.org/10.4102/ajlm.v8i1.786 Text en © 2019. The Authors https://creativecommons.org/licenses/by/4.0/ Licensee: AOSIS. This work is licensed under the Creative Commons Attribution License. |
spellingShingle | Brief Report Gobusamang, Ellen Nyepetsi, Naledi G. Motswaledi, Modisa S. Kasvosve, Ishmael Hyperuricaemia is associated with dyslipidemia but not HbA1c among type 2 diabetes mellitus patients in Botswana |
title | Hyperuricaemia is associated with dyslipidemia but not HbA1c among type 2 diabetes mellitus patients in Botswana |
title_full | Hyperuricaemia is associated with dyslipidemia but not HbA1c among type 2 diabetes mellitus patients in Botswana |
title_fullStr | Hyperuricaemia is associated with dyslipidemia but not HbA1c among type 2 diabetes mellitus patients in Botswana |
title_full_unstemmed | Hyperuricaemia is associated with dyslipidemia but not HbA1c among type 2 diabetes mellitus patients in Botswana |
title_short | Hyperuricaemia is associated with dyslipidemia but not HbA1c among type 2 diabetes mellitus patients in Botswana |
title_sort | hyperuricaemia is associated with dyslipidemia but not hba1c among type 2 diabetes mellitus patients in botswana |
topic | Brief Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852606/ https://www.ncbi.nlm.nih.gov/pubmed/31745455 http://dx.doi.org/10.4102/ajlm.v8i1.786 |
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