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Usefulness of narrow-band imaging in transurethral resection of bladder tumor: Early experience from a tertiary center in India

BACKGROUND: The current standard for diagnosis and treatment of urinary bladder cancer is transurethral resection of bladder tumor (TURBT) using white light guidance. Narrow band imaging (NBI) has emerged as a promising method for identifying additional bladder lesions. Various studies have been pub...

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Autores principales: Malik, Kanuj, Raja, Anand, Mahalingam, Sivakumar, Ravishankar, L. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852624/
https://www.ncbi.nlm.nih.gov/pubmed/31807483
http://dx.doi.org/10.4103/sajc.sajc_367_18
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author Malik, Kanuj
Raja, Anand
Mahalingam, Sivakumar
Ravishankar, L. S.
author_facet Malik, Kanuj
Raja, Anand
Mahalingam, Sivakumar
Ravishankar, L. S.
author_sort Malik, Kanuj
collection PubMed
description BACKGROUND: The current standard for diagnosis and treatment of urinary bladder cancer is transurethral resection of bladder tumor (TURBT) using white light guidance. Narrow band imaging (NBI) has emerged as a promising method for identifying additional bladder lesions. Various studies have been published to evaluate its sensitivity in identifying new lesions and its impact on decreasing recurrences. In this study, we evaluated our early experience using NBI in TURBTs. AIMS AND OBJECTIVE: The aim of the study is to determine the accuracy of NBI in identifying additional malignant lesions during TURBT. MATERIALS AND METHODS: We retrospectively collected data for all patients who underwent either TURBT or repeat TURBT with white light and NBI from November 2016 to July 2017 at Cancer Institute (WIA). The number of additional lesions identified using NBI was evaluated along with its correlation with the final histopathology. RESULTS: Forty patients were analysed of which 20 underwent TURBT and 20 underwent repeat TURBT. Of these, 36 patients had complete resection of tumour. Additional lesions were detected in 6 patients (14%) by NBI of which 2 (33%) were malignant histology. The additional lesions detected were carcinoma in situ and no patient was upstaged. CONCLUSION: The inclusion of NBI to conventional white light TURBT increases the sensitivity for identifying additional lesions. The limitation of NBI is high false positivity and its availability. Long term follow up studies with larger subset of patients are required to evaluate its role in decreasing recurrences and justification in routine clinical practice.
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spelling pubmed-68526242019-12-05 Usefulness of narrow-band imaging in transurethral resection of bladder tumor: Early experience from a tertiary center in India Malik, Kanuj Raja, Anand Mahalingam, Sivakumar Ravishankar, L. S. South Asian J Cancer ORIGINAL ARTICLE: Genitourinary Cancers BACKGROUND: The current standard for diagnosis and treatment of urinary bladder cancer is transurethral resection of bladder tumor (TURBT) using white light guidance. Narrow band imaging (NBI) has emerged as a promising method for identifying additional bladder lesions. Various studies have been published to evaluate its sensitivity in identifying new lesions and its impact on decreasing recurrences. In this study, we evaluated our early experience using NBI in TURBTs. AIMS AND OBJECTIVE: The aim of the study is to determine the accuracy of NBI in identifying additional malignant lesions during TURBT. MATERIALS AND METHODS: We retrospectively collected data for all patients who underwent either TURBT or repeat TURBT with white light and NBI from November 2016 to July 2017 at Cancer Institute (WIA). The number of additional lesions identified using NBI was evaluated along with its correlation with the final histopathology. RESULTS: Forty patients were analysed of which 20 underwent TURBT and 20 underwent repeat TURBT. Of these, 36 patients had complete resection of tumour. Additional lesions were detected in 6 patients (14%) by NBI of which 2 (33%) were malignant histology. The additional lesions detected were carcinoma in situ and no patient was upstaged. CONCLUSION: The inclusion of NBI to conventional white light TURBT increases the sensitivity for identifying additional lesions. The limitation of NBI is high false positivity and its availability. Long term follow up studies with larger subset of patients are required to evaluate its role in decreasing recurrences and justification in routine clinical practice. Wolters Kluwer - Medknow 2019 /pmc/articles/PMC6852624/ /pubmed/31807483 http://dx.doi.org/10.4103/sajc.sajc_367_18 Text en Copyright: © 2019 The South Asian Journal of Cancer http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle ORIGINAL ARTICLE: Genitourinary Cancers
Malik, Kanuj
Raja, Anand
Mahalingam, Sivakumar
Ravishankar, L. S.
Usefulness of narrow-band imaging in transurethral resection of bladder tumor: Early experience from a tertiary center in India
title Usefulness of narrow-band imaging in transurethral resection of bladder tumor: Early experience from a tertiary center in India
title_full Usefulness of narrow-band imaging in transurethral resection of bladder tumor: Early experience from a tertiary center in India
title_fullStr Usefulness of narrow-band imaging in transurethral resection of bladder tumor: Early experience from a tertiary center in India
title_full_unstemmed Usefulness of narrow-band imaging in transurethral resection of bladder tumor: Early experience from a tertiary center in India
title_short Usefulness of narrow-band imaging in transurethral resection of bladder tumor: Early experience from a tertiary center in India
title_sort usefulness of narrow-band imaging in transurethral resection of bladder tumor: early experience from a tertiary center in india
topic ORIGINAL ARTICLE: Genitourinary Cancers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852624/
https://www.ncbi.nlm.nih.gov/pubmed/31807483
http://dx.doi.org/10.4103/sajc.sajc_367_18
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