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Trastuzumab cotreatment improves survival of mice with PC‐3 prostate cancer xenografts treated with the GRPR antagonist (177)Lu‐DOTAGA‐PEG(2)‐RM26
Gastrin‐releasing peptide receptors (GRPRs) are overexpressed in prostate cancer and are suitable for targeted radionuclide therapy (TRT). We optimized the bombesin‐derived GRPR‐antagonist PEG(2)‐RM26 for labeling with (177)Lu and further determined the effect of treatment with (177)Lu‐labeled pepti...
Autores principales: | Mitran, Bogdan, Rinne, Sara S., Konijnenberg, Mark W., Maina, Theodosia, Nock, Berthold A., Altai, Mohamed, Vorobyeva, Anzhelika, Larhed, Mats, Tolmachev, Vladimir, de Jong, Marion, Rosenström, Ulrika, Orlova, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852655/ https://www.ncbi.nlm.nih.gov/pubmed/31077356 http://dx.doi.org/10.1002/ijc.32401 |
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