IgA and IgG1 Specific to Vi Polysaccharide of Salmonella Typhi Correlate With Protection Status in a Typhoid Fever Controlled Human Infection Model

Vaccination against Salmonella Typhi using the Vi capsular polysaccharide, a T-cell independent antigen, can protect from the development of typhoid fever. This implies that antibodies to Vi alone can protect in the absence of a T cell-mediated immune response; however, protective Vi antibodies have...

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Detalles Bibliográficos
Autores principales: Dahora, Lindsay C., Jin, Celina, Spreng, Rachel L., Feely, Frederick, Mathura, Ryan, Seaton, Kelly E., Zhang, Lu, Hill, Jennifer, Jones, Elizabeth, Alam, S. Munir, Dennison, S. Moses, Pollard, Andrew J., Tomaras, Georgia D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852708/
https://www.ncbi.nlm.nih.gov/pubmed/31781100
http://dx.doi.org/10.3389/fimmu.2019.02582

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