Folate deficiency induced H2A ubiquitination to lead to downregulated expression of genes involved in neural tube defects

BACKGROUND: Neural tube defects (NTDs) are common congenital malformations resulting in failure of the neural tube closure during early embryonic development. Although it is known that maternal folate deficiency increases the risk of NTDs, the mechanism remains elusive. RESULTS: Herein, we report th...

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Detalles Bibliográficos
Autores principales: Pei, Pei, cheng, Xiyue, Yu, Juan, Shen, Jinying, Li, Xue, Wu, Jianxin, Wang, Shan, Zhang, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852770/
https://www.ncbi.nlm.nih.gov/pubmed/31722724
http://dx.doi.org/10.1186/s13072-019-0312-7

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