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Identification of High-Affinity Small Molecule Targeting IDH2 for the Clinical Treatment of Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is symbolized by an increase in the number of myeloid cells in the bone marrow and an arrest in their maturation, frequently resulting in hematopoietic insufficiency (granulocytopenia, thrombocytopenia, or anemia) with or without leukocytosis either by a predominance of...

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Detalles Bibliográficos
Autores principales: Sweta, Jajoriya, Khandelwal, Ravina, Srinitha, Sivaraj, Pancholi, Rashi, Adhikary, Ritu, Ali, Meer Asif, Nayarisseri, Anuraj, Vuree, Sugunakar, Singh, Sanjeev Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852809/
https://www.ncbi.nlm.nih.gov/pubmed/31450897
http://dx.doi.org/10.31557/APJCP.2019.20.8.2287