Uncovering the Genomic Landscape in Newly Diagnosed and Relapsed Pediatric Cytogenetically Normal FLT 3‐ITD AML

Fms‐like tyrosine kinase 3 (FLT3) internal tandem duplication (ITD) mutations, common in pediatric acute myeloid leukemia (AML), associate with early relapse and poor prognosis. Past studies have suggested additional cooperative mutations are required for leukemogenesis in FLT3‐ITD+ AML. Using RNA s...

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Detalles Bibliográficos
Autores principales: Buelow, Daelynn R., Pounds, Stanley B., Wang, Yong‐Dong, Shi, Lei, Li, Yongjin, Finkelstein, David, Shurtleff, Sheila, Neale, Geoffrey, Inaba, Hiroto, Ribeiro, Raul C., Palumbo, Reid, Garrison, Dominique, Orwick, Shelley J., Blachly, James S., Kroll, Karl, Byrd, John C., Gruber, Tanja A., Rubnitz, Jeffrey E., Baker, Sharyn D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853146/
https://www.ncbi.nlm.nih.gov/pubmed/31350825
http://dx.doi.org/10.1111/cts.12669

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