OncodriveCLUSTL: a sequence-based clustering method to identify cancer drivers

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MOTIVATION: Identification of the genomic alterations driving tumorigenesis is one of the main goals in oncogenomics research. Given the evolutionary principles of cancer development, computational methods that detect signals of positive selection in the pattern of tumor mutations have been effectiv...

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Detalles Bibliográficos
Autores principales: Arnedo-Pac, Claudia, Mularoni, Loris, Muiños, Ferran, Gonzalez-Perez, Abel, Lopez-Bigas, Nuria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853674/
https://www.ncbi.nlm.nih.gov/pubmed/31228182
http://dx.doi.org/10.1093/bioinformatics/btz501

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