Cargando…
Discovering novel mutation signatures by latent Dirichlet allocation with variational Bayes inference
MOTIVATION: A cancer genome includes many mutations derived from various mutagens and mutational processes, leading to specific mutation patterns. It is known that each mutational process leads to characteristic mutations, and when a mutational process has preferences for mutations, this situation i...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853711/ https://www.ncbi.nlm.nih.gov/pubmed/30993319 http://dx.doi.org/10.1093/bioinformatics/btz266 |