Apolipoproteins and cancer

The role of apolipoproteins in cardiovascular disease has been well investigated, but their participation in cancer has only been explored in a few published studies which showed a close link with certain kinds of cancer. In this review, we focused on the function of different kinds of apolipoprotei...

Descripción completa

Detalles Bibliográficos
Autores principales: Ren, Liwen, Yi, Jie, Li, Wan, Zheng, Xiangjin, Liu, Jinyi, Wang, Jinhua, Du, Guanhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853823/
https://www.ncbi.nlm.nih.gov/pubmed/31573738
http://dx.doi.org/10.1002/cam4.2587
_version_ 1783470105765609472
author Ren, Liwen
Yi, Jie
Li, Wan
Zheng, Xiangjin
Liu, Jinyi
Wang, Jinhua
Du, Guanhua
author_facet Ren, Liwen
Yi, Jie
Li, Wan
Zheng, Xiangjin
Liu, Jinyi
Wang, Jinhua
Du, Guanhua
author_sort Ren, Liwen
collection PubMed
description The role of apolipoproteins in cardiovascular disease has been well investigated, but their participation in cancer has only been explored in a few published studies which showed a close link with certain kinds of cancer. In this review, we focused on the function of different kinds of apolipoproteins in cancers, autophagy, oxidative stress, and drug resistance. The potential application of apolipoproteins as biomarkers for cancer diagnosis and prognosis was highlighted, together with an investigation of their potential as drug targets for cancer treatment. Many important roles of apolipoproteins and their mechanisms in cancers were reviewed in detail and future perspectives of apolipoprotein research were discussed.
format Online
Article
Text
id pubmed-6853823
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-68538232019-12-16 Apolipoproteins and cancer Ren, Liwen Yi, Jie Li, Wan Zheng, Xiangjin Liu, Jinyi Wang, Jinhua Du, Guanhua Cancer Med Cancer Biology The role of apolipoproteins in cardiovascular disease has been well investigated, but their participation in cancer has only been explored in a few published studies which showed a close link with certain kinds of cancer. In this review, we focused on the function of different kinds of apolipoproteins in cancers, autophagy, oxidative stress, and drug resistance. The potential application of apolipoproteins as biomarkers for cancer diagnosis and prognosis was highlighted, together with an investigation of their potential as drug targets for cancer treatment. Many important roles of apolipoproteins and their mechanisms in cancers were reviewed in detail and future perspectives of apolipoprotein research were discussed. John Wiley and Sons Inc. 2019-10-01 /pmc/articles/PMC6853823/ /pubmed/31573738 http://dx.doi.org/10.1002/cam4.2587 Text en © 2019 The Authors. Cancer Medicine published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Cancer Biology
Ren, Liwen
Yi, Jie
Li, Wan
Zheng, Xiangjin
Liu, Jinyi
Wang, Jinhua
Du, Guanhua
Apolipoproteins and cancer
title Apolipoproteins and cancer
title_full Apolipoproteins and cancer
title_fullStr Apolipoproteins and cancer
title_full_unstemmed Apolipoproteins and cancer
title_short Apolipoproteins and cancer
title_sort apolipoproteins and cancer
topic Cancer Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853823/
https://www.ncbi.nlm.nih.gov/pubmed/31573738
http://dx.doi.org/10.1002/cam4.2587
work_keys_str_mv AT renliwen apolipoproteinsandcancer
AT yijie apolipoproteinsandcancer
AT liwan apolipoproteinsandcancer
AT zhengxiangjin apolipoproteinsandcancer
AT liujinyi apolipoproteinsandcancer
AT wangjinhua apolipoproteinsandcancer
AT duguanhua apolipoproteinsandcancer

Ejemplares similares