Cargando…
Determinants of participation and detection rate of upper gastrointestinal cancer from population‐based screening program in China
Upper gastrointestinal cancer (UGC) screening has been widely implemented in many Asian countries. However, there is little evidence of participation and diagnostic yields in population‐based UGC screening in China. The participation rate and detection of upper gastrointestinal lesions in this progr...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853828/ https://www.ncbi.nlm.nih.gov/pubmed/31560836 http://dx.doi.org/10.1002/cam4.2578 |
_version_ | 1783470106944208896 |
---|---|
author | Guo, Lanwei Zhang, Shaokai Liu, Shuzheng Zheng, Liyang Chen, Qiong Cao, Xiaoqin Sun, Xibin Qiao, Youlin Zhang, Jiangong |
author_facet | Guo, Lanwei Zhang, Shaokai Liu, Shuzheng Zheng, Liyang Chen, Qiong Cao, Xiaoqin Sun, Xibin Qiao, Youlin Zhang, Jiangong |
author_sort | Guo, Lanwei |
collection | PubMed |
description | Upper gastrointestinal cancer (UGC) screening has been widely implemented in many Asian countries. However, there is little evidence of participation and diagnostic yields in population‐based UGC screening in China. The participation rate and detection of upper gastrointestinal lesions in this program were reported and related factors were explored. The analysis was conducted in the context of the Cancer Screening Program in Urban China, which recruited 179 002 eligible participants aged 40‐74 years from three cities in Henan province from 2013 to 2017. A total of 43 423 participants were evaluated to be high risk for esophageal cancer or gastric cancer by an established risk score system and were subsequently recommended for endoscopy. Of 43 423 with high risk for UGC, 7996 subjects undertook endoscopy (participation rate of 18.4%). We found that male sex, high level of education, marriage, smoking, current alcohol drinking, lack of physical activity, history of upper gastrointestinal system disease, and family history of UGC were associated with increased participation of endoscopy screening. Overall, 15 UGC (0.19%), 275 squamous epithelial dysplasia (3.44%), and 33 intraepithelial neoplasm (0.41%) cases were detected. Several factors including age, sex, smoking, current alcohol drinking, lack of physical activity, and dietary intake of processed meat were identified to be associated with the presence of upper gastrointestinal lesions. Health promotion campaigns targeting the specific group of individuals identified in our study will be helpful for improvement of the adherence of UGC screening in population‐based cancer screening programs. Participant rate and yield of UGC screening will provide important references for evaluating the effectiveness and cost‐effectiveness of cancer screening in China. |
format | Online Article Text |
id | pubmed-6853828 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-68538282019-12-16 Determinants of participation and detection rate of upper gastrointestinal cancer from population‐based screening program in China Guo, Lanwei Zhang, Shaokai Liu, Shuzheng Zheng, Liyang Chen, Qiong Cao, Xiaoqin Sun, Xibin Qiao, Youlin Zhang, Jiangong Cancer Med Cancer Prevention Upper gastrointestinal cancer (UGC) screening has been widely implemented in many Asian countries. However, there is little evidence of participation and diagnostic yields in population‐based UGC screening in China. The participation rate and detection of upper gastrointestinal lesions in this program were reported and related factors were explored. The analysis was conducted in the context of the Cancer Screening Program in Urban China, which recruited 179 002 eligible participants aged 40‐74 years from three cities in Henan province from 2013 to 2017. A total of 43 423 participants were evaluated to be high risk for esophageal cancer or gastric cancer by an established risk score system and were subsequently recommended for endoscopy. Of 43 423 with high risk for UGC, 7996 subjects undertook endoscopy (participation rate of 18.4%). We found that male sex, high level of education, marriage, smoking, current alcohol drinking, lack of physical activity, history of upper gastrointestinal system disease, and family history of UGC were associated with increased participation of endoscopy screening. Overall, 15 UGC (0.19%), 275 squamous epithelial dysplasia (3.44%), and 33 intraepithelial neoplasm (0.41%) cases were detected. Several factors including age, sex, smoking, current alcohol drinking, lack of physical activity, and dietary intake of processed meat were identified to be associated with the presence of upper gastrointestinal lesions. Health promotion campaigns targeting the specific group of individuals identified in our study will be helpful for improvement of the adherence of UGC screening in population‐based cancer screening programs. Participant rate and yield of UGC screening will provide important references for evaluating the effectiveness and cost‐effectiveness of cancer screening in China. John Wiley and Sons Inc. 2019-09-27 /pmc/articles/PMC6853828/ /pubmed/31560836 http://dx.doi.org/10.1002/cam4.2578 Text en © 2019 The Authors. Cancer Medicine published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Cancer Prevention Guo, Lanwei Zhang, Shaokai Liu, Shuzheng Zheng, Liyang Chen, Qiong Cao, Xiaoqin Sun, Xibin Qiao, Youlin Zhang, Jiangong Determinants of participation and detection rate of upper gastrointestinal cancer from population‐based screening program in China |
title | Determinants of participation and detection rate of upper gastrointestinal cancer from population‐based screening program in China |
title_full | Determinants of participation and detection rate of upper gastrointestinal cancer from population‐based screening program in China |
title_fullStr | Determinants of participation and detection rate of upper gastrointestinal cancer from population‐based screening program in China |
title_full_unstemmed | Determinants of participation and detection rate of upper gastrointestinal cancer from population‐based screening program in China |
title_short | Determinants of participation and detection rate of upper gastrointestinal cancer from population‐based screening program in China |
title_sort | determinants of participation and detection rate of upper gastrointestinal cancer from population‐based screening program in china |
topic | Cancer Prevention |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853828/ https://www.ncbi.nlm.nih.gov/pubmed/31560836 http://dx.doi.org/10.1002/cam4.2578 |
work_keys_str_mv | AT guolanwei determinantsofparticipationanddetectionrateofuppergastrointestinalcancerfrompopulationbasedscreeningprograminchina AT zhangshaokai determinantsofparticipationanddetectionrateofuppergastrointestinalcancerfrompopulationbasedscreeningprograminchina AT liushuzheng determinantsofparticipationanddetectionrateofuppergastrointestinalcancerfrompopulationbasedscreeningprograminchina AT zhengliyang determinantsofparticipationanddetectionrateofuppergastrointestinalcancerfrompopulationbasedscreeningprograminchina AT chenqiong determinantsofparticipationanddetectionrateofuppergastrointestinalcancerfrompopulationbasedscreeningprograminchina AT caoxiaoqin determinantsofparticipationanddetectionrateofuppergastrointestinalcancerfrompopulationbasedscreeningprograminchina AT sunxibin determinantsofparticipationanddetectionrateofuppergastrointestinalcancerfrompopulationbasedscreeningprograminchina AT qiaoyoulin determinantsofparticipationanddetectionrateofuppergastrointestinalcancerfrompopulationbasedscreeningprograminchina AT zhangjiangong determinantsofparticipationanddetectionrateofuppergastrointestinalcancerfrompopulationbasedscreeningprograminchina |