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Prolonged PSA stabilization and overall survival following sipuleucel-T monotherapy in metastatic castration-resistant prostate cancer patients
BACKGROUND: Sipuleucel-T is an autologous cellular immunotherapy that is FDA approved for the treatment of asymptomatic or minimally symptomatic metastatic castrate-resistant prostate cancer (mCRPC). The IMPACT registry trial demonstrated a 4.1 month survival benefit, but not a consistent PSA respon...
Autores principales: | Holl, Eda K., McNamara, Megan A., Healy, Patrick, Anand, Monika, Concepcion, Raoul S., Breland, Coleman D., Dumbudze, Igor, Tutrone, Ron, Shore, Neal, Armstrong, Andrew J., Harrison, Michael, Wallace, Joe A., Wu, Yuan, George, Daniel J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853838/ https://www.ncbi.nlm.nih.gov/pubmed/30980027 http://dx.doi.org/10.1038/s41391-019-0144-3 |
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