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Tumor necrosis factor induces rapid down-regulation of TXNIP in human T cells
In addition to antigen-driven signals, T cells need co-stimulatory signals for robust activation. Several receptors, including members of the tumor necrosis factor receptor superfamily (TNFRSF), can deliver co-stimulatory signals to T cells. Thioredoxin interacting protein (TXNIP) is an important in...
Autores principales: | Levring, Trine B., Kongsbak-Wismann, Martin, Rode, Anna K. O., Al-Jaberi, Fatima A. H., Lopez, Daniel V., Met, Özcan, Woetmann, Anders, Bonefeld, Charlotte M., Ødum, Niels, Geisler, Carsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853882/ https://www.ncbi.nlm.nih.gov/pubmed/31723203 http://dx.doi.org/10.1038/s41598-019-53234-x |
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