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Rapid evolution and biogeographic spread in a colorectal cancer

How and when tumoral clones start spreading to surrounding and distant tissues is currently unclear. Here we leveraged a model-based evolutionary framework to investigate the demographic and biogeographic history of a colorectal cancer. Our analyses strongly support an early monoclonal metastatic co...

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Detalles Bibliográficos
Autores principales: Alves, Joao M., Prado-López, Sonia, Cameselle-Teijeiro, José Manuel, Posada, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853914/
https://www.ncbi.nlm.nih.gov/pubmed/31723138
http://dx.doi.org/10.1038/s41467-019-12926-8