Development of a Staphylococcus aureus reporter strain with click beetle red luciferase for enhanced in vivo imaging of experimental bacteremia and mixed infections

In vivo bioluminescence imaging has been used to monitor Staphylococcus aureus infections in preclinical models by employing bacterial reporter strains possessing a modified lux operon from Photorhabdus luminescens. However, the relatively short emission wavelength of lux (peak 490 nm) has limited t...

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Detalles Bibliográficos
Autores principales: Miller, Robert J., Crosby, Heidi A., Schilcher, Katrin, Wang, Yu, Ortines, Roger V., Mazhar, Momina, Dikeman, Dustin A., Pinsker, Bret L., Brown, Isabelle D., Joyce, Daniel P., Zhang, Jeffrey, Archer, Nathan K., Liu, Haiyun, Alphonse, Martin P., Czupryna, Julie, Anderson, William R., Bernthal, Nicholas M., Fortuno-Miranda, Lea, Bulte, Jeff W. M., Francis, Kevin P., Horswill, Alexander R., Miller, Lloyd S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853927/
https://www.ncbi.nlm.nih.gov/pubmed/31723175
http://dx.doi.org/10.1038/s41598-019-52982-0

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