Cargando…

Mapping the perturbome network of cellular perturbations

Drug combinations provide effective treatments for diverse diseases, but also represent a major cause of adverse reactions. Currently there is no systematic understanding of how the complex cellular perturbations induced by different drugs influence each other. Here, we introduce a mathematical fram...

Descripción completa

Detalles Bibliográficos
Autores principales: Caldera, Michael, Müller, Felix, Kaltenbrunner, Isabel, Licciardello, Marco P., Lardeau, Charles-Hugues, Kubicek, Stefan, Menche, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853941/
https://www.ncbi.nlm.nih.gov/pubmed/31723137
http://dx.doi.org/10.1038/s41467-019-13058-9