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Nutritional status modifies pregnane X receptor regulated transcriptome

Pregnane X receptor (PXR) regulates glucose and lipid metabolism, but little is known of the nutritional regulation of PXR function. We investigated the genome wide effects of the nutritional status on the PXR mediated gene regulation in the liver. Mice were treated with a PXR ligand pregnenolone 16...

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Detalles Bibliográficos
Autores principales:	Hassani-Nezhad-Gashti, Fatemeh, Kummu, Outi, Karpale, Mikko, Rysä, Jaana, Hakkola, Jukka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853963/ https://www.ncbi.nlm.nih.gov/pubmed/31723190 http://dx.doi.org/10.1038/s41598-019-53101-9

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