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Multiple Pathways To Avoid Beta Interferon Sensitivity of HIV-1 by Mutations in Capsid

Type I interferons (IFNs), including alpha IFN (IFN-α) and IFN-β, potently suppress HIV-1 replication by upregulating IFN-stimulated genes (ISGs). The viral capsid protein (CA) partly determines the sensitivity of HIV-1 to IFNs. However, it remains to be determined whether CA-related functions, incl...

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Detalles Bibliográficos
Autores principales:	Sultana, Tahmina, Mamede, João I., Saito, Akatsuki, Ode, Hirotaka, Nohata, Kyotaro, Cohen, Romy, Nakayama, Emi E., Iwatani, Yasumasa, Yamashita, Masahiro, Hope, Thomas J., Shioda, Tatsuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Virus-Cell Interactions
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854511/ https://www.ncbi.nlm.nih.gov/pubmed/31511380 http://dx.doi.org/10.1128/JVI.00986-19

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