Cargando…

IL-1β increases the expression of inflammatory factors in synovial fluid-derived fibroblast-like synoviocytes via activation of the NF-κB-mediated ERK-STAT1 signaling pathway

Interleukin (IL)-1β serves a crucial role in the progression of rheumatoid arthritis. Previous studies have indicated that the ERK/STAT1 signaling pathway may be involved in the inflammatory response in synovial fluid-derived fibroblast-like synoviocytes (sfd-FLSs). However, the molecular mechanisms...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Jie, Wang, Junhu, Liang, Xiaojun, Zhao, Hongmou, Lu, Jun, Ma, Qiang, Jing, Bingfei, Tian, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854543/ https://www.ncbi.nlm.nih.gov/pubmed/31638264 http://dx.doi.org/10.3892/mmr.2019.10759

Ejemplares similares

The synovial proteome: analysis of fibroblast-like synoviocytes
por: Dasuri, Kumar, et al.
Publicado: (2004)

Phenotypic and functional characterization of synovial fluid-derived fibroblast-like synoviocytes in rheumatoid arthritis
por: Køster, Ditte, et al.
Publicado: (2021)

NF-κB signaling in rheumatoid arthritis with focus on fibroblast-like synoviocytes
por: Nejatbakhsh Samimi, Leila, et al.
Publicado: (2020)

Non-Transcriptional and Translational Function of Canonical NF-κB Signaling in Activating ERK1/2 in IL-1β-Induced COX-2 Expression in Synovial Fibroblasts
por: Nakano, Rei, et al.
Publicado: (2020)

The synovial fluid fibroblast-like synoviocyte: A long-neglected piece in the puzzle of rheumatoid arthritis pathogenesis
por: Mahmoud, Dorra Elhaj, et al.
Publicado: (2022)

Oleanolic Acid Decreases IL-1β-Induced Activation of Fibroblast-Like Synoviocytes via the SIRT3-NF-κB Axis in Osteoarthritis
por: Bao, Jiapeng, et al.
Publicado: (2020)

ERK2 and JNK1 contribute to TNF-α-induced IL-8 expression in synovial fibroblasts
por: Namba, Shinichi, et al.
Publicado: (2017)

Flt3 inhibition leads to decreased production of IL-6 by synovial biopsies and fibroblast-like synoviocytes by reducing NFKb activity
por: Ramos, M Inês, et al.
Publicado: (2011)

p53 predominantly regulates IL-6 production and suppresses synovial inflammation in fibroblast-like synoviocytes and adjuvant-induced arthritis
por: Zhang, Ting, et al.
Publicado: (2016)

Fibronectin-1 is a dominant mechanism for rheumatoid arthritis via the mediation of synovial fibroblasts activity
por: Yang, Jie, et al.
Publicado: (2022)

Increased HIF-1α in Knee Osteoarthritis Aggravate Synovial Fibrosis via Fibroblast-Like Synoviocyte Pyroptosis
por: Zhang, Li, et al.
Publicado: (2019)

An osteoarthritis subtype characterized by synovial lipid metabolism disorder and fibroblast-like synoviocyte dysfunction
por: Cao, Xu, et al.
Publicado: (2022)

SIRT1 inhibits rheumatoid arthritis fibroblast-like synoviocyte aggressiveness and inflammatory response via suppressing NF-κB pathway
por: Li, Guoqing, et al.
Publicado: (2018)

Production and Secretion of Gelsolin by Both Human Macrophage- and Fibroblast-like Synoviocytes and GSN Modulation in the Synovial Fluid of Patients with Various Forms of Arthritis
por: Feldt, Jessica, et al.
Publicado: (2022)

Activation of synovial fibroblasts by laminin-1 and transforming growth factor beta induces expression of stromelysins independently of TNFα, IL-1β or NF-κB
por: Warstat, Katrin, et al.
Publicado: (2007)

The synovial cadherin (cadherin-11) mediates tissue formation and promotes invasion of fibroblast-like synoviocytes
por: Kiener, H, et al.
Publicado: (2003)

The involvement of follistatin-like protein 1 in osteoarthritis by elevating NF-κB-mediated inflammatory cytokines and enhancing fibroblast like synoviocyte proliferation
por: Ni, Su, et al.
Publicado: (2015)

PRP from Personal Blood Relieves Joint Fluid-Inducing Synovial Injury through NF-κB Pathway and Mitochondrial Apoptosis in Human Synovial Fibroblast Cells
por: Xie, Li, et al.
Publicado: (2022)

Synovial fibroblast‐targeting liposomes encapsulating an NF‐κB‐blocking peptide ameliorates zymosan‐induced synovial inflammation
por: You, Changcheng, et al.
Publicado: (2018)

A novel NF-κB/YY1/microRNA-10a regulatory circuit in fibroblast-like synoviocytes regulates inflammation in rheumatoid arthritis
por: Mu, Nan, et al.
Publicado: (2016)

Increased AP-1 and NF-κB activation and recruitment with the combination of the proinflammatory cytokines IL-1β, tumor necrosis factor alpha and IL-17 in rheumatoid synoviocytes
por: Granet, Corinne, et al.
Publicado: (2004)

IMMUNOHISTOLOGIC STUDIES OF SYNOVIOCYTES AND SYNOVIAL EXUDATE CELLS
por: Hurd, Eric R., et al.
Publicado: (1971)

A representative metalloprotease induces PGE(2) synthesis in fibroblast-like synoviocytes via the NF-κB/COX-2 pathway with amplification by IL-1β and the EP4 receptor
por: Viana, Mariana N., et al.
Publicado: (2020)

JNK activation is essential for activation of MEK/ERK signaling in IL-1β-induced COX-2 expression in synovial fibroblasts
por: Kitanaka, Taku, et al.
Publicado: (2017)

Aspirin promotes apoptosis and inhibits proliferation by blocking G(0)/G(1) into S phase in rheumatoid arthritis fibroblast-like synoviocytes via downregulation of JAK/STAT3 and NF-κB signaling pathway
por: Zhang, Xiaoqi, et al.
Publicado: (2018)

Retracted: PRP from Personal Blood Relieves Joint Fluid-Inducing Synovial Injury through NF-κB Pathway and Mitochondrial Apoptosis in Human Synovial Fibroblast Cells
por: International, BioMed Research
Publicado: (2023)

IL-17 induces production of IL-6 and IL-8 in rheumatoid arthritis synovial fibroblasts via NF-κB- and PI3-kinase/Akt-dependent pathways
por: Hwang, Sue-Yun, et al.
Publicado: (2004)

Expression of Concern: SIRT1 inhibits rheumatoid arthritis fibroblast-like synoviocyte aggressiveness and inflammatory response via suppressing NF-κB pathway
Publicado: (2023)

Shikonin attenuates rheumatoid arthritis by targeting SOCS1/JAK/STAT signaling pathway of fibroblast like synoviocytes
por: He, Lianhua, et al.
Publicado: (2021)

Total glucosides of peony induce fibroblast-like synovial apoptosis, and ameliorate cartilage injury via blocking the NF-κB/STAT3 pathway
por: Fu, Min, et al.
Publicado: (2022)

CX3CL1 promotes MMP-3 production via the CX3CR1, c-Raf, MEK, ERK, and NF-κB signaling pathway in osteoarthritis synovial fibroblasts
por: Hou, Sheng-Mou, et al.
Publicado: (2017)

Punicalagin Inhibited Inflammation and Migration of Fibroblast-Like Synoviocytes Through NF-κB Pathway in the Experimental Study of Rheumatoid Arthritis
por: Huang, Mingcheng, et al.
Publicado: (2021)

Umbelliferone and scopoletin target tyrosine kinases on fibroblast-like synoviocytes to block NF-κB signaling to combat rheumatoid arthritis
por: Chen, Qilei, et al.
Publicado: (2022)

Imperatorin Inhibits Proliferation, Migration, and Inflammation via Blocking the NF-κB and MAPK Pathways in Rheumatoid Fibroblast-like Synoviocytes
por: Lin, Wei, et al.
Publicado: (2022)

E2F2 directly regulates the STAT1 and PI3K/AKT/NF-κB pathways to exacerbate the inflammatory phenotype in rheumatoid arthritis synovial fibroblasts and mouse embryonic fibroblasts
por: Wang, Shiguan, et al.
Publicado: (2018)

Nesfatin-1 facilitates IL-1β production in osteoarthritis synovial fibroblasts by suppressing miR-204-5p synthesis through the AP-1 and NF-κB pathways
por: Lee, Kun-Tsan, et al.
Publicado: (2021)

Joint Location–Specific JAK‐STAT Signaling in Rheumatoid Arthritis Fibroblast‐like Synoviocytes
por: Hammaker, Deepa, et al.
Publicado: (2019)

IL-1 but not IL-18 induces osteoprotegerin and TRAIL in rheumatoid arthritis synovial fibroblasts
por: Morel, J, et al.
Publicado: (2003)

Thrombospondin 2 Promotes IL-6 Production in Osteoarthritis Synovial Fibroblasts via the PI3K/AKT/NF-κB Pathway
por: Hou, Chun-Han, et al.
Publicado: (2021)

IL-17-mediated Bcl-2 expression regulates survival of fibroblast-like synoviocytes in rheumatoid arthritis through STAT3 activation
por: Lee, Seon-Yeong, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_uh5co5ktm93cc8cfq83ef0rc7f