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Curcumin relieves paraquat-induced lung injury through inhibiting the thioredoxin interacting protein/NLR pyrin domain containing 3-mediated inflammatory pathway

When paraquat (PQ) enters the human body, it increases oxidative stress and inflammation, ultimately resulting in acute lung injury (ALI). Curcumin, a naturally occurring compound, has been reported to ameliorate PQ-induced ALI; however, the underlying molecular mechanisms remain unclear. In the pre...

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Detalles Bibliográficos
Autores principales: Ren, Yi, Yang, Zhizhou, Sun, Zhaorui, Zhang, Wei, Chen, Xin, Nie, Shinan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854544/
https://www.ncbi.nlm.nih.gov/pubmed/31485636
http://dx.doi.org/10.3892/mmr.2019.10612