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HIV-1 integrase inhibitors targeting various DDE transposases: Retroviral integration versus RAG-mediated recombination

Transposases are ubiquitous mobile genetic elements responsible for genome development, driving rearrangements, such as insertions, deletions and translocations. Across species evolution, some transposases are tamed by their host and are made part of complex cellular systems. The proliferation of re...

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Detalles Bibliográficos
Autores principales: Mușat, Mihaela Georgiana, Nițulescu, George Mihai, Surleac, Marius, Tsatsakis, Aristidis, Spandidos, Demetrios A., Margină, Denisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854553/
https://www.ncbi.nlm.nih.gov/pubmed/31702817
http://dx.doi.org/10.3892/mmr.2019.10777

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