Mouse APOBEC1 cytidine deaminase can induce somatic mutations in chromosomal DNA

BACKGROUND: APOBEC1 (A1) enzymes are cytidine deaminases involved in RNA editing. In addition to this activity, a few A1 enzymes have been shown to be active on single stranded DNA. As two human ssDNA cytidine deaminases APOBEC3A (A3A), APOBEC3B (A3B) and related enzymes across the spectrum of place...

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Detalles Bibliográficos
Autores principales: Caval, Vincent, Jiao, Wenjuan, Berry, Noémie, Khalfi, Pierre, Pitré, Emmanuelle, Thiers, Valérie, Vartanian, Jean-Pierre, Wain-Hobson, Simon, Suspène, Rodolphe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854741/
https://www.ncbi.nlm.nih.gov/pubmed/31726973
http://dx.doi.org/10.1186/s12864-019-6216-x

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