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Synthesis of Organometallic Oligonucleotides through Oximation with Metalated Benzaldehydes
[Image: see text] A phthaloyl-protected aminooxymethyl-C-2′-deoxyriboside building block has been prepared and incorporated in the middle of an oligodeoxyribonucleotide. Removal of the phthaloyl protection followed by on-support oximation with either mercurated or palladated benzaldehydes yielded ol...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854833/ https://www.ncbi.nlm.nih.gov/pubmed/31737842 http://dx.doi.org/10.1021/acsomega.9b02804 |
| Sumario: | [Image: see text] A phthaloyl-protected aminooxymethyl-C-2′-deoxyriboside building block has been prepared and incorporated in the middle of an oligodeoxyribonucleotide. Removal of the phthaloyl protection followed by on-support oximation with either mercurated or palladated benzaldehydes yielded oligonucleotides bearing the respective benzaldoxime metallacycles. |
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