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EZH2 negatively regulates PD-L1 expression in hepatocellular carcinoma

BACKGROUND: Accumulating studies suggest that targeting epigenetic modifications could improve the efficacy of tumor immunotherapy; however, the mechanisms underlying this phenomenon remain largely unknown. Here, we investigated the ability of the epigenetic modifier, enhancer of zeste 2 polycomb re...

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Detalles Bibliográficos
Autores principales: Xiao, Gang, Jin, Li-Lian, Liu, Chao-Qun, Wang, Yong-Chun, Meng, Ya-Ming, Zhou, Zhong-Guo, Chen, Jing, Yu, Xing-Juan, Zhang, Yao-Jun, Xu, Jing, Zheng, Limin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854886/
https://www.ncbi.nlm.nih.gov/pubmed/31727135
http://dx.doi.org/10.1186/s40425-019-0784-9