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Transcriptome Analysis of Hypertrophic Heart Tissues from Murine Transverse Aortic Constriction and Human Aortic Stenosis Reveals Key Genes and Transcription Factors Involved in Cardiac Remodeling Induced by Mechanical Stress

BACKGROUND: Mechanical stress-induced cardiac remodeling that results in heart failure is characterized by transcriptional reprogramming of gene expression. However, a systematic study of genomic changes involved in this process has not been performed to date. To investigate the genomic changes and...

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Detalles Bibliográficos
Autores principales: Yu, Peng, Zhang, Baoli, Liu, Ming, Yu, Ying, Zhao, Ji, Zhang, Chunyu, Li, Yana, Zhang, Lei, Yang, Xue, Jiang, Hong, Zou, Yunzeng, Ge, Junbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854968/
https://www.ncbi.nlm.nih.gov/pubmed/31772688
http://dx.doi.org/10.1155/2019/5058313