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Mast Cell Degranulation Decreases Lipopolysaccharide-Induced Aortic Gene Expression and Systemic Levels of Interleukin-6 In Vivo

Mast cells play an important role in immunomodulation and in the maintenance of vascular integrity. Interleukin-6 (IL-6) is one of the key biomarkers and therapeutic target in systemic vasculitis. The objective of the current study is to describe the role of mast cells in arterial IL-6 homeostasis....

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Detalles Bibliográficos
Autores principales: Springer, Jason M., Raveendran, Vineesh V., Zhang, Mingcai, Funk, Ryan, Smith, Donald D., Maz, Mehrdad, Dileepan, Kottarappat N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6855011/
https://www.ncbi.nlm.nih.gov/pubmed/31780858
http://dx.doi.org/10.1155/2019/3856360

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