A Novel Liposome Formulation Carrying Both an Insulin Peptide and a Ligand for Invariant Natural Killer T Cells Induces Accumulation of Regulatory T Cells to Islets in Nonobese Diabetic Mice

Type 1 diabetes (T1D) is an autoimmune disease caused by the destruction of pancreatic β cells by autoantigen-reactive diabetogenic cells. Antigen-specific therapies using islet autoantigens for restoring immune tolerance have emerged as promising approaches for the treatment of T1D but have been un...

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Detalles Bibliográficos
Autores principales: Akimoto, Hidetoshi, Fukuda-Kawaguchi, Emi, Duramad, Omar, Ishii, Yasuyuki, Tanabe, Kazunari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6855036/
https://www.ncbi.nlm.nih.gov/pubmed/31781669
http://dx.doi.org/10.1155/2019/9430473

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