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A novel machine learning-derived radiotranscriptomic signature of perivascular fat improves cardiac risk prediction using coronary CT angiography
BACKGROUND: Coronary inflammation induces dynamic changes in the balance between water and lipid content in perivascular adipose tissue (PVAT), as captured by perivascular Fat Attenuation Index (FAI) in standard coronary CT angiography (CCTA). However, inflammation is not the only process involved i...
Autores principales: | Oikonomou, Evangelos K, Williams, Michelle C, Kotanidis, Christos P, Desai, Milind Y, Marwan, Mohamed, Antonopoulos, Alexios S, Thomas, Katharine E, Thomas, Sheena, Akoumianakis, Ioannis, Fan, Lampson M, Kesavan, Sujatha, Herdman, Laura, Alashi, Alaa, Centeno, Erika Hutt, Lyasheva, Maria, Griffin, Brian P, Flamm, Scott D, Shirodaria, Cheerag, Sabharwal, Nikant, Kelion, Andrew, Dweck, Marc R, Van Beek, Edwin J R, Deanfield, John, Hopewell, Jemma C, Neubauer, Stefan, Channon, Keith M, Achenbach, Stephan, Newby, David E, Antoniades, Charalambos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6855141/ https://www.ncbi.nlm.nih.gov/pubmed/31504423 http://dx.doi.org/10.1093/eurheartj/ehz592 |
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