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Experimental Reproduction of Dynamic Fluctuation of TSH Receptor–Binding Antibodies Between Stimulation and Inhibition

CONTEXT: Hyperthyroidism in Graves disease (GD) is caused by autoantibody stimulation of the TSH receptor (TSHR). TSHR autoantibody (TSHR-Ab) activity is measured routinely by inhibition of labeled ligand (TSH or M22) binding to the TSHR [TSH-binding inhibitory immunoglobulins (TBIIs)] or by stimula...

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Detalles Bibliográficos
Autores principales:	Tagami, Tetsuya, Hiroshima-Hamanaka, Kaho, Umakoshi, Hironobu, Tsuiki-Naruse, Mika, Kusakabe, Toru, Satoh-Asahara, Noriko, Shimatsu, Akira, Moriyama, Kenji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Endocrine Society 2019
Materias:	Clinical Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6855214/ https://www.ncbi.nlm.nih.gov/pubmed/31745531 http://dx.doi.org/10.1210/js.2019-00012

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