Cargando…

Quantification of the severity of hypoxic-ischemic brain injury in a neonatal preclinical model using measurements of cytochrome-c-oxidase from a miniature broadband-near-infrared spectroscopy system

We describe the development of a miniaturized broadband near-infrared spectroscopy system (bNIRS), which measures changes in cerebral tissue oxyhemoglobin ([Formula: see text]) and deoxyhemoglobin ([HHb]) plus tissue metabolism via changes in the oxidation state of cytochrome-c-oxidase ([oxCCO]). Th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kaynezhad, Pardis, Mitra, Subhabrata, Bale, Gemma, Bauer, Cornelius, Lingam, Ingran, Meehan, Christopher, Avdic-Belltheus, Adnan, Martinello, Kathryn A., Bainbridge, Alan, Robertson, Nicola J., Tachtsidis, Ilias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society of Photo-Optical Instrumentation Engineers 2019
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6855218/ https://www.ncbi.nlm.nih.gov/pubmed/31737744 http://dx.doi.org/10.1117/1.NPh.6.4.045009

Ejemplares similares

Broadband NIRS Cerebral Cytochrome-C-Oxidase Response to Anoxia Before and After Hypoxic-Ischaemic Injury in Piglets
por: Bale, Gemma, et al.
Publicado: (2018)

Proton Magnetic Resonance Spectroscopy Lactate/N-Acetylaspartate Within 48 h Predicts Cell Death Following Varied Neuroprotective Interventions in a Piglet Model of Hypoxia–Ischemia With and Without Inflammation-Sensitization
por: Pang, Raymand, et al.
Publicado: (2020)

Interrelationship Between Broadband NIRS Measurements of Cerebral Cytochrome C Oxidase and Systemic Changes Indicates Injury Severity in Neonatal Encephalopathy
por: Bale, Gemma, et al.
Publicado: (2016)

Acute LPS sensitization and continuous infusion exacerbates hypoxic brain injury in a piglet model of neonatal encephalopathy
por: Martinello, Kathryn A., et al.
Publicado: (2019)

Simultaneous monitoring of cerebral perfusion and cytochrome c oxidase by combining broadband near-infrared spectroscopy and diffuse correlation spectroscopy
por: Rajaram, Ajay, et al.
Publicado: (2018)

Absolute quantification of cerebral tissue oxygen saturation with multidistance broadband NIRS in newborn brain
por: Kovacsova, Zuzana, et al.
Publicado: (2021)

High-Dose Melatonin and Ethanol Excipient Combined with Therapeutic Hypothermia in a Newborn Piglet Asphyxia Model
por: Robertson, Nicola J., et al.
Publicado: (2020)

Early assessment of injury with optical markers in a piglet model of neonatal encephalopathy
por: Harvey-Jones, Kelly, et al.
Publicado: (2023)

Optical monitoring of retinal respiration in real time: 670 nm light increases the redox state of mitochondria
por: Kaynezhad, Pardis, et al.
Publicado: (2016)

Human umbilical cord mesenchymal stromal cells as an adjunct therapy with therapeutic hypothermia in a piglet model of perinatal asphyxia
por: Robertson, Nicola J., et al.
Publicado: (2021)

Hypothermia is not therapeutic in a neonatal piglet model of inflammation-sensitized hypoxia–ischemia
por: Martinello, Kathryn A., et al.
Publicado: (2021)

Cerebral Near Infrared Spectroscopy Monitoring in Term Infants With Hypoxic Ischemic Encephalopathy—A Systematic Review
por: Mitra, Subhabrata, et al.
Publicado: (2020)

Watching the human retina breath in real time and the slowing of mitochondrial respiration with age
por: Kaynezhad, Pardis, et al.
Publicado: (2023)

Changes in Cytochrome-C-Oxidase Account for Changes in Attenuation of Near-Infrared Light in the Healthy Infant Brain
por: Siddiqui, M. F., et al.
Publicado: (2018)

Image reconstruction of oxidized cerebral cytochrome C oxidase changes from broadband near-infrared spectroscopy data
por: Brigadoi, Sabrina, et al.
Publicado: (2017)

Functional NIRS Measurement of Cytochrome-C-Oxidase Demonstrates a More Brain-Specific Marker of Frontal Lobe Activation Compared to the Haemoglobins
por: de Roever, Isabel, et al.
Publicado: (2017)

The Role of Neuroglobin in Retinal Hemodynamics and Metabolism: A Real-Time Study
por: Kaynezhad, Pardis, et al.
Publicado: (2022)

In Vivo Measurement of Cerebral Mitochondrial Metabolism Using Broadband Near Infrared Spectroscopy Following Neonatal Stroke
por: Mitra, Subhabrata, et al.
Publicado: (2015)

Analysis of the Changes in the Oxidation of Brain Tissue Cytochrome c Oxidase in Traumatic Brain Injury Patients during Hypercapnoea: a Broadband NIRS Study
por: Tachtsidis, Ilias, et al.
Publicado: (2011)

Watching synchronous mitochondrial respiration in the retina and its instability in a mouse model of macular degeneration
por: Kaynezhad, Pardis, et al.
Publicado: (2021)

Relationship Between Cerebral Oxygenation and Metabolism During Rewarming in Newborn Infants After Therapeutic Hypothermia Following Hypoxic-Ischemic Brain Injury
por: Mitra, Subhabrata, et al.
Publicado: (2016)

Changes in Cerebral Oxidative Metabolism during Neonatal Seizures Following Hypoxic–Ischemic Brain Injury
por: Mitra, Subhabrata, et al.
Publicado: (2016)

Metabolic brain measurements in the newborn: Advances in optical technologies
por: Bale, Gemma, et al.
Publicado: (2020)

Spatial Distribution of Changes in Oxidised Cytochrome C Oxidase During Visual Stimulation Using Broadband Near Infrared Spectroscopy Imaging
por: Phan, P., et al.
Publicado: (2016)

ABroAD: A Machine Learning Based Approach to Detect Broadband NIRS Artefacts
por: Russell-Buckland, Joshua, et al.
Publicado: (2018)

Investigation of the quantification of hemoglobin and cytochrome-c-oxidase in the exposed cortex with near-infrared hyperspectral imaging: a simulation study
por: Giannoni, Luca, et al.
Publicado: (2020)

Pressure passivity of cerebral mitochondrial metabolism is associated with poor outcome following perinatal hypoxic ischemic brain injury
por: Mitra, Subhabrata, et al.
Publicado: (2017)

Modelling of mitochondrial oxygen consumption and NIRS detection of cytochrome oxidase redox state
por: Banaji, Murad, et al.
Publicado: (2010)

Melatonin and/or erythropoietin combined with hypothermia in a piglet model of perinatal asphyxia
por: Pang, Raymand, et al.
Publicado: (2020)

Non-invasive measurement of a metabolic marker of infant brain function
por: Siddiqui, Maheen F., et al.
Publicado: (2017)

Prediction of brain tissue temperature using near-infrared spectroscopy
por: Holper, Lisa, et al.
Publicado: (2017)

Dependence on NIRS Source-Detector Spacing of Cytochrome c Oxidase Response to Hypoxia and Hypercapnia in the Adult Brain
por: Kolyva, Christina, et al.
Publicado: (2013)

Reduction of Cytochrome c Oxidase During Vasovagal Hypoxia-Ischemia in Human Adult Brain: A Case Study
por: Ghosh, Arnab, et al.
Publicado: (2013)

Normobaric Hyperoxia Does Not Change Optical Scattering or Pathlength but Does Increase Oxidised Cytochrome c Oxidase Concentration in Patients with Brain Injury
por: Ghosh, Arnab, et al.
Publicado: (2012)

Systematic investigation of changes in oxidized cerebral cytochrome c oxidase concentration during frontal lobe activation in healthy adults
por: Kolyva, Christina, et al.
Publicado: (2012)

Use of a Hybrid Optical Spectrometer for the Measurement of Changes in Oxidized Cytochrome c Oxidase Concentration and Tissue Scattering During Functional Activation
por: Ghosh, Arnab, et al.
Publicado: (2012)

Cytochrome c oxidase response to changes in cerebral oxygen delivery in the adult brain shows higher brain-specificity than haemoglobin()
por: Kolyva, Christina, et al.
Publicado: (2014)

Investigation of the Pattern of the Hemodynamic Response as Measured by Functional Near-Infrared Spectroscopy (fNIRS) Studies in Newborns, Less Than a Month Old: A Systematic Review
por: de Roever, Isabel, et al.
Publicado: (2018)

Broadband-NIRS System Identifies Epileptic Focus in a Child with Focal Cortical Dysplasia—A Case Study
por: Vezyroglou, Aikaterini, et al.
Publicado: (2022)

Depth-resolved assessment of changes in concentration of chromophores using time-resolved near-infrared spectroscopy: estimation of cytochrome-c-oxidase uncertainty by Monte Carlo simulations
por: Sudakou, Aleh, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_jfq4rt1j7qaahmieksenavffih