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Genotype-matched Newcastle disease virus vaccine confers improved protection against genotype XII challenge: The importance of cytoplasmic tails in viral replication and vaccine design
Although typical Newcastle disease virus (NDV) vaccines can prevent mortality, they are not effective in preventing viral shedding. To overcome this, genotype-matched vaccines have been proposed. To date, this approach has never been tested against genotype XII strains. In this study, we generated a...
Autores principales: | Izquierdo-Lara, Ray, Chumbe, Ana, Calderón, Katherine, Fernández-Díaz, Manolo, Vakharia, Vikram N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6855454/ https://www.ncbi.nlm.nih.gov/pubmed/31725727 http://dx.doi.org/10.1371/journal.pone.0209539 |
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