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Restrained expansion of the recall germinal center response as biomarker of protection for influenza vaccination in mice

Correlates of protection (CoP) are invaluable for iterative vaccine design studies, especially in pursuit of complex vaccines such as a universal influenza vaccine (UFV) where a single antigen is optimized to elicit broad protection against many viral antigenic variants. Since broadly protective ant...

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Detalles Bibliográficos
Autores principales: Kil, Laurens P., Vaneman, Joost, van der Lubbe, Joan E. M., Czapska-Casey, Dominika, Tolboom, Jeroen T. B. M., Roozendaal, Ramon, Zahn, Roland C., Kuipers, Harmjan, Solforosi, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6855462/
https://www.ncbi.nlm.nih.gov/pubmed/31725776
http://dx.doi.org/10.1371/journal.pone.0225063