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Building gene regulatory networks from scATAC-seq and scRNA-seq using Linked Self Organizing Maps
Rapid advances in single-cell assays have outpaced methods for analysis of those data types. Different single-cell assays show extensive variation in sensitivity and signal to noise levels. In particular, scATAC-seq generates extremely sparse and noisy datasets. Existing methods developed to analyze...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6855564/ https://www.ncbi.nlm.nih.gov/pubmed/31682608 http://dx.doi.org/10.1371/journal.pcbi.1006555 |