Cargando…

Coincident Activation of Glutamate Receptors Enhances GABA(A) Receptor-Induced Ionic Plasticity of the Intracellular Cl(−)-Concentration in Dissociated Neuronal Cultures

Massive activation of γ-amino butyric acid A (GABA(A)) receptors during pathophysiological activity induces an increase in the intracellular Cl(−)-concentration ([Cl(−)](i)), which is sufficient to render GABAergic responses excitatory. However, to what extent physiological levels of GABAergic activ...

Descripción completa

Detalles Bibliográficos
Autores principales: Halbhuber, Lisa, Achtner, Cécilia, Luhmann, Heiko J., Sinning, Anne, Kilb, Werner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856009/
https://www.ncbi.nlm.nih.gov/pubmed/31787883
http://dx.doi.org/10.3389/fncel.2019.00497